This was the product of Emanuel Thomas Lyon starting around 1850. An ad in 1853 (see below) indicated that his business was at 161 Broadway, New York City. This was the same address the business was at when Demas Barnes was the Proprietor. An ad in 1873 indicated he (they) had over 30 years experience. It was sold by Demas Barnes & Co. during that time - he worked for them. Later, Heath, Wyncoop & Co. took over proprietorship (1859). The Lyon Mfg Co. registered the brand name "Kathairon" as a Trade Mark in 1893. The Proprietors at that time said that the brand name had been in use since 1850. Lyon's Kathairon was still listed for sale at least as late as 1906. A label on a bottle after 1906 said it was 76.25% alcohol (view) - Yeah! The box from that one also had statements in three other languages (view), so it's reasonable to assume it was being sold internationally.